BM_2026v17n3

Bioscience Methods 2026, Vol.17, No.3, 199-207 http://bioscipublisher.com/index.php/bm 204 antioxidant potential of the phytoconstituents present in tea seed oil, which may suppress reactive oxygen species generation and promote the restoration of redox balance (Yan et al., 2020). 5 Conclusions This study affirms the therapeutic potential of TSO in effectively reducing blood pressure, enhancing antioxidant defenses and improving lipid profiles. Although further investigation is warranted to elucidate the underlying mechanisms, the study provides valuable insights into the multifaceted benefits of TSO, positioning it as a natural and potentially effective agent in the management of hypertension and its associated complications. List of abbreviations Abbreviation Full name TSO Tea Seed Oil L-NAME NG-nitro-L-arginine Methyl Ester SBP Systolic Blood Pressure DBP Diastolic Blood Pressure MAP Mean Arterial Pressure ALT Alanine Aminotransferase AST Aspartate Aminotransferase ALP Alkaline Phosphatase HDL-C High-Density Lipoprotein Cholesterol LDL-C Low-Density Lipoprotein Cholesterol TC Total Cholesterol TGs Triglycerides GSH Glutathione GPx Glutathione Peroxidase SOD Superoxide Dismutase MDA Malondialdehyde NO Nitric Oxide NOS Nitric Oxide Synthase GGT γ-glutamyltransferase ACE Angiotensin-Converting Enzyme TP Total Protein ALB Albumin TB Total Bilirubin ANOVA Analysis of Variance Availability of data and materials The datasets used and/or analyzed during the current study are available from the corresponding author on resonable rquest. Competing interests The authors declare no conflict of interest. Ethics approval and consent to participate Authors declared that all experiments were carried out with strict compliance to the “Principle of Laboratory Animal Care” and ethical guidelines for investigation of experimental pain in conscious animals. The project was approved by the University of Ibadan Animal Care and Use Research Ethics Committee. Funding This project was funded by the authors and the management of Cocoa Research Institute of Nigeria (CRIN). Authors’ Contributions LEY: Conceptualization, supervision and final correction of draft. JFA and AAO: Methodology, data collection, writing-original draft preparation. LEY and JFA: Editing. All authors have read and approved the final manuscript.

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